8-Bromo-GTP

(8Br-GTP)

Product Specifications

CAS Number

23197-98-0

Product Name Alternative

(8Br-GTP), 8-Bromo-guanosine-5'-triphosphate, Sodium salt

Concentration

10 mM-11 mM

Purity

≥ 95% (HPLC)

Form

Solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5

Smiles

Nc1[nH]c (=O) c2c (n (c (Br) n2) [C@@H]2O[C@H] (COP (=O) (O) OP (=O) (O) OP (=O) (O) O) [C@@H] (O) [C@H]2O) n1

Molecular Formula

C10H15N5O14P3Br

Molecular Weight

Theoretical MW: 602.08 g/mol (free acid) ; Detected MW: 600.90 g/mol (free acid)

Storage Conditions

Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible

Notes

For research use only.

Applications Notes

Inhibition of RNA triphosphatases; Inhibition of GTP-hydrolases; Conformational studies on syn-anti dynamics of GTP. Spectroscopic Propertie: λmax 259 nm, ε 14.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5) . Specific Ligands: Yeast RNA triphosphates, Cytoskeletal protein FtsZ and tubulin.