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Mant-GTP

Mant-GTP

Product Specifications

CAS Number

148821-03-8

Product Name Alternative

2'/3'-O- (N-Methyl-anthraniloyl) -guanosine-5'-triphosphate, Triethylammonium salt

Concentration

10 mM-11 mM

Purity

≥ 95% (HPLC)

Form

Solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5

Smiles

OP (=O) (O) OP (=O) (O) OP (=O) (O) OC[C@H]1O[C@@H] (n2c3c (nc2) c (=O) [nH]c (n3) N) [C@H] (OC (=O) c2c (NC) cccc2) [C@@H]1O.OP (=O) (O) OP (=O) (O) OP (=O) (O) OC[C@H]1O[C@@H] (n2c3c (nc2) c (=O) [nH]c (n3) N) [C@H] (O) [C@@H]1OC (=O) c1c (cccc1) NC

Molecular Formula

C18H23N6O15P3

Molecular Weight

Theoretical MW: 656.33 g/mol (free acid) ; Detected MW: 656.04 g/mol (free acid)

Storage Conditions

Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible

Notes

For research use only.

Applications Notes

Inhibition of AC-isoform and GTPs; Activity measurement: GC; Specifity measurements with isoforms of ACs; FRET: AC, edema factor; Inhibition of edema factor (anthrax) . Spectroscopic Propertie: λmax 252/355 nm, ε 22.6/5.7 L mmol-1 cm-1, (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm.

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