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TNP-ATP

TNP-ATP

Product Specifications

CAS Number

120360-48-7

Product Name Alternative

2',3'-O-Trinitrophenyl-adenosine-5'-triphosphate, Triethylammonium salt

Concentration

10 mM-11 mM

Purity

≥ 95% (HPLC)

Form

Solution in water; Color: orange; pH: 7.5 ± 0.5

Smiles

OP (=O) (O) OP (=O) (O) OP (=O) (O) OC[C@H]1O[C@@H] (n2cnc3c (N) ncnc23) [C@@H]2OC3 (O[C@H]12) C (=C/C (=[N+] (\O) /[O-]) /C=C3N (=O) =O) N (=O) =O

Molecular Formula

C16H17N8O19P3

Molecular Weight

Theoretical MW: 718.27 g/mol; Detected MW: 717.98 g/mol

Storage Conditions

Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible

Notes

For research use only.

Applications Notes

Agonistic ligand, mainly for nucleoside receptor A1 Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. The ester form is protected during uptake and transport and can be well-directed released through activation. Spectroscopic Propertie: λmax 259/408/470 nm, ε 25.0/26.4/18.5 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 408/470 nm, λem 552 nm. Specific Ligands: Ligand for purinergic receptors: P2X1, P2X 2, Antagonist for purinergic receptors: P2X1, P2X 3, P2X 4, P2X.

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