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NPE-caged-ATP

NPE-caged-ATP

Product Specifications

CAS Number

67030-27-7

Product Name Alternative

Adenosine-5'-triphosphate, P3- (1- (2-nitrophenyl) -ethyl) -ester, Sodium salt

Concentration

10 mM-11 mM

Purity

≥ 95% (HPLC)

Form

Solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5

Smiles

[C@@H]1 ([C@H] ([C@@H] (O[C@@H]1COP (=O) (OP (=O) (OP (=O) (OC (c1ccccc1[N+] (=O) [O-]) C) O) O) O) n1c2c (nc1) c (ncn2) N) O) O

Molecular Formula

C18H23N6O15P3

Molecular Weight

Theoretical MW: 656.33 g/mol (free acid) ; Detected MW: 656.04 g/mol (free acid)

Storage Conditions

Store at -20 °C. store dark. Short term exposure (up to 1 week cumulative) to ambient temperature possible

Notes

For research use only.

Applications Notes

Determination of quantum yield and irradiation conditions. Time resolved solid state NMR Ligand for purinergic receptors: The nucleotide can be transported extra-or intracellular in a protected form to the target. After activation by well-defined conditions the liberated ATP can interact with P2X-and P2Y-receptors. Agonistic ligand, mainly for nucleoside receptor A1 Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. The caged form is protected during uptake and transport in animal experiments and can be well-directed released through activation at the target tissue. Spectroscopic Propertie: λmax 260 nm, ε 18.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5) .

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