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AppCp

(AMPPCP)

Product Specifications

CAS Number

7414-56-4

Product Name Alternative

(AMPPCP), Adenosine-5'-[ (β, γ) -methyleno]triphosphate, Sodium salt

Purity

≥ 95% (HPLC)

Form

Solid; Color: white to off-white

Smiles

OP (=O) (O) CP (=O) (O) OP (=O) (O) OC[C@H]1O[C@@H] (n2c3c (nc2) c (N) ncn3) [C@H] (O) [C@@H]1O

Molecular Formula

C11H18N5O12P3

Molecular Weight

Theoretical MW: 505.21 g/mol (free acid) ; Detected MW: 505.02 g/mol (free acid)

Storage Conditions

Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible

Notes

For research use only.

Applications Notes

Conformational studies on complex with mevalonate diphosphate decarboxylase; Structure of the complex with folylpolyglutamate synthetase; Structure of complex with p90 ribosomal S6 kinases; Crystal structure of complex with Ca2+-ATPase; NMR-studies of complex with yeast hexokinase; Agonistic ligand, mainly for nucleoside receptor A1 Nucleosidephosphates stabilized against hydrolytic degradation can directly bind to nucleoside receptors. Spectroscopic Propertie: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl, pH 7.5) . Specific Ligands: Tubulin, Nonhydrolyzable ligand for P2X purinoreceptor.

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