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AP3G (A cap) - Solid

(ApppG), GP3A, GpppA, G (5') ppp (5') A

Product Specifications

Product Name Alternative

(ApppG), GP3A, GpppA, G (5') ppp (5') A, P1- (5'-Adenosyl) P3- (5'-guanosyl) triphosphate, Sodium salt

Purity

≥ 95% (HPLC)

Form

Solid; Color: white to off-white

Smiles

O=c1[nH]c (N) nc2c1ncn2[C@@H]1O[C@H] (COP (=O) (OP (=O) (OP (=O) (OC[C@@H]2[C@H] ([C@H] ([C@@H] (O2) n2c3c (nc2) c (ncn3) N) O) O) O) O) O) [C@@H] (O) [C@H]1O

Molecular Formula

C20H27N10O17P3

Molecular Weight

Theoretical MW: 772.41 g/mol (free acid) ; Detected MW: 772.08 g/mol (free acid)

Storage Conditions

Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible

Notes

For research use only.

Applications Notes

Synthesis of mRNA with a non-functional cap analog (ApppG) to estimate the level of cap-independent translation; Investigation of stress related (Near UV and oxidation) product formation in bacteria. Spectroscopic Propertie: λ 259 nm, ε 27.0 L mmol-1 cm-1 (Tris-HCl pH, 7.5) .

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