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DPBQ

DPBQ (ZINC1620467) is a p53-activating small molecule that induces apoptosis specifically in polyploid cells. Its mechanism is distinct from topoisomerase inhibition or direct DNA binding. This compound serves as a research tool for studying p53 pathways in oncology, with applications in both in vitro and in vivo models of polyploidy-related diseases.

Product Specifications

CAS Number

7029-89-2

Product Name Alternative

DPBQ, 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione, p53, ZINC 1620467, ZINC1620467, ZINC-1620467

Field of Research

Cell Biology

Purity

98.08% (May vary between batches)

Solubility

DMSO:2.5 mg/mL (6.9 mM)

Smiles

O=C1c2ccccc2C (=O) c2nc (-c3ccccc3) c (nc12) -c1ccccc1

Molecular Formula

C24H14N2O2

Molecular Weight

362.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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