PF-06305591
PF-06305591 is a potent and selective small molecule inhibitor of the voltage-gated sodium channel NaV1.8, exhibiting an IC50 of 15 nM. This compound is a valuable research tool for investigating pain pathways and neuropathic mechanisms in both in vitro electrophysiology studies and in vivo animal models.
Product Specifications
CAS Number
1449473-97-5
Product Name Alternative
NaV1.8, Sodium Channel, SodiumChannel, PF6305591, PF-6305591, PF 6305591, PF 06305591, PF06305591, PF-06305591
Field of Research
Pharmacology & Drug Discovery
Purity
99.85% (May vary between batches)
Solubility
DMSO:45 mg/mL (164.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.29 mM)
Smiles
C[C@H] ([C@H] (N) c1nc2cc (ccc2[nH]1) C (C) (C) C) C (N) =O
Molecular Formula
C15H22N4O
Molecular Weight
274.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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