Salinomycin
Salinomycin (Procoxacin) is a polyether ionophore antibiotic active against gram-positive bacteria. It potently inhibits the Wnt/β-catenin pathway by blocking LRP6 phosphorylation and selectively targets cancer stem cells, making it a valuable tool for oncology and stem cell research in both in vitro and in vivo models.
Product Specifications
CAS Number
53003-10-4
Product Name Alternative
Beta-catenin, betacatenin, bcatenin, Antibacterial, βcatenin, Salinomycin, Wnt/b-catenin, Wnt, Procoxacin, Wnt/β-catenin, Wnt/betacatenin
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.34% (May vary between batches)
Solubility
DMSO:140 mg/mL (186.42 mM)
Smiles
[H][C@@]1 (CC[C@H] (C) [C@@] ([H]) (O1) [C@@H] (C) [C@H] (O) [C@H] (C) C (=O) [C@H] (CC) [C@@]1 ([H]) O[C@@]2 (O[C@@]3 (CC[C@] (C) (O3) [C@@]3 ([H]) CC[C@] (O) (CC) [C@H] (C) O3) [C@H] (O) C=C2) [C@H] (C) C[C@@H]1C) [C@@H] (CC) C (O) =O
Molecular Formula
C42H70O11
Molecular Weight
751
Storage Conditions
-20°C
Notes
For research use only.
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