20 (S) -Hydroxycholesterol
20 (S) -Hydroxycholesterol is a potent endogenous allosteric activator of the Smoothened (Smo) receptor, a key component of the Hedgehog signaling pathway. This oxysterol is a valuable research tool for investigating Hedgehog pathway activation in both cellular assays and model organism studies.
Product Specifications
CAS Number
516-72-3
Product Name Alternative
20α-Hydroxycholesterol, 20Hydroxycholesterol, 20alpha-Hydroxycholesterol, 20a-Hydroxycholesterol, hSmo, Human Endogenous Metabolite
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Smoothened agonist
Form
Powder
Solubility
Soluble in DMSO or in Ethanol.
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) C (=CC3) C[C@@H] (O) CC4) (CC1) [H]) [H]) (CC[C@@]2 ([C@@] (CCCC (C) C) (C) O) [H]) [H]
Molecular Formula
C27H46O2
Molecular Weight
402.66
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5-Cholesten-3β, 20α-diol
Available Sizes
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