4'-Ethynyl-2'-deoxyadenosine
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a potent nucleoside reverse transcriptase inhibitor effective against drug-resistant HIV-1 strains, with an EC50 of 98 nM in MT-4 cells. It serves as a key research tool for investigating antiviral mechanisms and resistance profiles in both cellular and biochemical assays.
Product Specifications
CAS Number
306305-07-7
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
NC1=C2C (N (C=N2) [C@@H]3O[C@] (C#C) (CO) [C@@H] (O) C3) =NC=N1
Molecular Formula
C12H13N5O3
Molecular Weight
275.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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