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4'-Ethynyl-2'-deoxyadenosine

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a potent nucleoside reverse transcriptase inhibitor effective against drug-resistant HIV-1 strains, with an EC50 of 98 nM in MT-4 cells. It serves as a key research tool for investigating antiviral mechanisms and resistance profiles in both cellular and biochemical assays.

Product Specifications

CAS Number

306305-07-7

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Smiles

NC1=C2C (N (C=N2) [C@@H]3O[C@] (C#C) (CO) [C@@H] (O) C3) =NC=N1

Molecular Formula

C12H13N5O3

Molecular Weight

275.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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