6RK73
6RK73 is a potent, covalent, and irreversible inhibitor that selectively targets UCHL1 with an IC50 of 0.23 μM, demonstrating over 1000-fold selectivity against UCHL3. This small molecule is a valuable chemical probe for studying deubiquitinase function in neurodegenerative disease models and cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
1895050-66-4
Product Name Alternative
6RK73, 6RK-73
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
99.91% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.01 mM) ; DMSO:112.5 mg/mL (366.01 mM)
Smiles
O=C (Nc1ncc (s1) N1CCOCC1) [C@H]1CCN (C1) C#N
Molecular Formula
C13H17N5O2S
Molecular Weight
307.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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