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Aβ42-IN-1

Aβ42-IN-1 (compound 1v) is a novel, orally bioavailable γ-secretase modulator that potently lowers Aβ42 levels (IC50 = 0.091 μM) in cellular assays without inhibiting CYP3A4. It exhibits a sustained pharmacokinetic profile, supporting its utility for in vivo research in Alzheimer's disease and related neurodegenerative fields.

Product Specifications

CAS Number

2582757-69-3

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Smiles

O=C (C1=NC=C (C2=C (C) N=C3C (OCC4=CC=C (C5=CC=CC=C5) C=C4) =CC=CN32) C=C1) NCC.[H]Cl

Molecular Formula

C29H27ClN4O2

Molecular Weight

499

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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