Aβ42-IN-1
Aβ42-IN-1 (compound 1v) is a novel, orally bioavailable γ-secretase modulator that potently lowers Aβ42 levels (IC50 = 0.091 μM) in cellular assays without inhibiting CYP3A4. It exhibits a sustained pharmacokinetic profile, supporting its utility for in vivo research in Alzheimer's disease and related neurodegenerative fields.
Product Specifications
CAS Number
2582757-69-3
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
O=C (C1=NC=C (C2=C (C) N=C3C (OCC4=CC=C (C5=CC=CC=C5) C=C4) =CC=CN32) C=C1) NCC.[H]Cl
Molecular Formula
C29H27ClN4O2
Molecular Weight
499
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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