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LSN2839567

LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of the CDK4/6 inhibitor Abemaciclib, also inhibiting CDK9. It demonstrates concentration-dependent inhibition of cell growth and cycle progression in vitro, making it a valuable research tool for studying cancers such as breast and lung cancer.

Product Specifications

CAS Number

1231930-57-6

Product Name Alternative

CDK9, CDK6, CDK4, Abemaciclib metabolite M2, Abemaciclib metabolite M-2, Abemaciclib Metabolites M2

Field of Research

Cell Biology, Metabolism Research

Purity

99.14% (May vary between batches)

Solubility

DMSO:1 mg/mL (2.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.09 mM)

Smiles

CC (C) n1c (C) nc2c (F) cc (cc12) -c1nc (Nc2ccc (CN3CCNCC3) cn2) ncc1F

Molecular Formula

C25H28F2N8

Molecular Weight

478.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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