LSN2839567
LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of the CDK4/6 inhibitor Abemaciclib, also inhibiting CDK9. It demonstrates concentration-dependent inhibition of cell growth and cycle progression in vitro, making it a valuable research tool for studying cancers such as breast and lung cancer.
Product Specifications
CAS Number
1231930-57-6
Product Name Alternative
CDK9, CDK6, CDK4, Abemaciclib metabolite M2, Abemaciclib metabolite M-2, Abemaciclib Metabolites M2
Field of Research
Cell Biology, Metabolism Research
Purity
99.14% (May vary between batches)
Solubility
DMSO:1 mg/mL (2.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.09 mM)
Smiles
CC (C) n1c (C) nc2c (F) cc (cc12) -c1nc (Nc2ccc (CN3CCNCC3) cn2) ncc1F
Molecular Formula
C25H28F2N8
Molecular Weight
478.54
Storage Conditions
-20°C
Notes
For research use only.
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