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ACP-5862

ACP-5862 is the major active metabolite of Acalabrutinib, featuring a pyrrolidine ring-opened structure and exhibiting potent BTK inhibition (IC50: 5.0 nM) . This metabolite is valuable for research into the pharmacokinetics, efficacy, and mechanism of action of BTK inhibitors in both cellular and animal models of B-cell malignancies.

Product Specifications

CAS Number

2230757-47-6

Field of Research

Cardiovascular Research, Metabolism Research, Signal Transduction

Smiles

CC#CC (=O) NCCCC (=O) c1nc (-c2ccc (cc2) C (=O) Nc2ccccn2) c2c (N) nccn12

Molecular Formula

C26H23N7O3

Molecular Weight

481.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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