ACP-5862
ACP-5862 is the major active metabolite of Acalabrutinib, featuring a pyrrolidine ring-opened structure and exhibiting potent BTK inhibition (IC50: 5.0 nM) . This metabolite is valuable for research into the pharmacokinetics, efficacy, and mechanism of action of BTK inhibitors in both cellular and animal models of B-cell malignancies.
Product Specifications
CAS Number
2230757-47-6
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Smiles
CC#CC (=O) NCCCC (=O) c1nc (-c2ccc (cc2) C (=O) Nc2ccccn2) c2c (N) nccn12
Molecular Formula
C26H23N7O3
Molecular Weight
481.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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