ACY-1083
ACY-1083 is a potent, selective, and brain-penetrant HDAC6 inhibitor with an IC50 of 3 nM. It is a valuable research tool for studying HDAC6 biology and has demonstrated efficacy in preclinical models for reversing chemotherapy-induced peripheral neuropathy.
Product Specifications
CAS Number
1708113-43-2
Product Name Alternative
HDAC6, ACY 1083, ACY1083, ACY-1083
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.35 mM) ; DMSO:237.5 mg/mL (681.79 mM)
Smiles
ONC (=O) c1cnc (NC2 (CCC (F) (F) CC2) c2ccccc2) nc1
Molecular Formula
C17H18F2N4O2
Molecular Weight
348.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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