AGN 196996
AGN 196996 is a highly potent and selective RARα antagonist with a Ki of 2 nM, demonstrating minimal activity at RARβ and RARγ. This selectivity makes it a valuable chemical probe for investigating RARα-specific signaling in retinoid research, applicable in both cellular and animal models of differentiation and disease.
Product Specifications
CAS Number
958295-17-5
Product Name Alternative
Autophagy, AGN196996, AGN-196996, AGN 196996, RARα, RARβ, RARγ, Retinoid Receptor, RetinoidReceptor
Field of Research
Cell Biology, Metabolism Research
Purity
98.74% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (6.84 mM) ; DMSO:225 mg/mL (466.5 mM)
Smiles
CCOc1c (Br) cc (cc1C (=O) c1ccc (C) cc1) C (=O) Nc1ccc (cc1) C (O) =O
Molecular Formula
C24H20BrNO5
Molecular Weight
482.32
Storage Conditions
-20°C
Notes
For research use only.
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