AKT-IN-3
AKT-IN-3 is a potent, orally bioavailable pan-Akt inhibitor with low hERG liability, demonstrating low nanomolar IC50 values against Akt1/2/3. It also inhibits several other AGC kinases, including PKA and PKC. This profile supports its use in cancer research for investigating PI3K/Akt pathway signaling in both cellular and animal models.
Product Specifications
CAS Number
2374740-21-1
Field of Research
Cell Biology, Signal Transduction
Smiles
CNC (=O) C[C@@H]1C[C@H] ([C@@H] (CN1) NC (=O) c1cc (c (Cl) o1) -c1c (Cl) cnn1C) c1ccc (F) c (F) c1
Molecular Formula
C23H23Cl2F2N5O3
Molecular Weight
526.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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