Apcin-A
Apcin-A is a cell-permeable inhibitor of the anaphase-promoting complex/cyclosome (APC/C) that acts by binding to its coactivator Cdc20, thereby blocking the ubiquitination of Cdc20-specific substrates. This compound serves as a valuable chemical probe for cell cycle research and is a key component in the synthesis of the PROTAC molecule CP5V for targeted protein degradation studies.
Product Specifications
CAS Number
1683617-62-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
NCCCOC (=O) NC (Nc1ncccn1) C (Cl) (Cl) Cl
Molecular Formula
C10H14Cl3N5O2
Molecular Weight
342.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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