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Apcin-A

Apcin-A is a cell-permeable inhibitor of the anaphase-promoting complex/cyclosome (APC/C) that acts by binding to its coactivator Cdc20, thereby blocking the ubiquitination of Cdc20-specific substrates. This compound serves as a valuable chemical probe for cell cycle research and is a key component in the synthesis of the PROTAC molecule CP5V for targeted protein degradation studies.

Product Specifications

CAS Number

1683617-62-0

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

NCCCOC (=O) NC (Nc1ncccn1) C (Cl) (Cl) Cl

Molecular Formula

C10H14Cl3N5O2

Molecular Weight

342.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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