AR-A 2
AR-A 2 is a potent and selective 5-HT1B receptor antagonist, exhibiting high affinity for guinea pig cortical 5-HT1B/1D and recombinant 5-HT1B receptors with Kis of 0.24 nM and 0.47 nM, respectively, and a 10-fold lower affinity for the 5-HT1D receptor. This compound is a valuable pharmacological tool for investigating serotonin receptor function in both in vitro binding assays and in vivo models of CNS disorders.
Product Specifications
CAS Number
220051-79-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
CC1=C2C (=C (C=C1) N3CCN (C) CC3) C[C@H] (NC (=O) C4=CC=C (C=C4) N5CCOCC5) CC2
Molecular Formula
C27H36N4O2
Molecular Weight
448.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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Capsule Filter, NY, 0.45μm, 1/4" Nptm, 1/Pk
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