Anisodamine (hydrobromide)

Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties[1][2].

Product Specifications

CAS Number

[55449-49-5]

Product Name Alternative

6-Hydroxyhyoscyamine (hydrobromide)

UNSPSC

12352005

Hazard Statement

H300+H330

Target

MAChR

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/anisodamine-hydrobromide.html

Purity

99.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN1[C@H]2[C@@H](O)C[C@@H]1C[C@H](OC([C@@H](C3=CC=CC=C3)CO)=O)C2.Br

Molecular Formula

C17H24BrNO4

Molecular Weight

386.28

Precautions

H300+H330

References & Citations

[1]Eisenkraft A. Possible role for anisodamine in organophosphate poisoning. Br J Pharmacol. 2016;173 (11) :1719-1727.|[2]Liu C, et al. Antishock effect of anisodamine involves a novel pathway for activating alpha7 nicotinic acetylcholine receptor. Crit Care Med. 2009;37 (2) :634-641.