AS2717638
AS2717638 is a potent and selective oral antagonist of the lysophosphatidic acid receptor 5 (LPA5), exhibiting an IC50 of 38 nM against the human target. It has demonstrated efficacy in preclinical models, significantly reducing allodynia induced by PGF2α, PGE2, and AMPA, supporting its research use in studying neuropathic pain pathways.
Product Specifications
CAS Number
2148339-28-8
Product Name Alternative
HLPA5, AS2717638, AS-2717638, AS 2717638
Field of Research
Pharmacology & Drug Discovery
Purity
98.67% (May vary between batches)
Solubility
DMSO:54 mg/mL (120.68 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.17 mM)
Smiles
COc1cc2c (cn (-c3noc4ccc (C) cc34) c (=O) c2cc1OC) C (=O) N1CCCCC1
Molecular Formula
C25H25N3O5
Molecular Weight
447.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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