ASP-4058
ASP-4058 is a second-generation, orally bioavailable agonist selectively targeting S1P1 and S1P5 receptors. It demonstrates efficacy in preclinical models, notably ameliorating experimental autoimmune encephalomyelitis (EAE) in mice, supporting its research application in neuroinflammatory and autoimmune disease studies.
Product Specifications
CAS Number
952565-91-2
Product Name Alternative
ASP 4058, ASP4058, ASP-4058, LPLReceptor, LPL Receptor, S1P Receptor, S1P5, S1PReceptor, S1P1
Field of Research
Pharmacology & Drug Discovery
Purity
99.30% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.52 mM) ; DMSO:70 mg/mL (158.26 mM)
Smiles
C[C@H] (Oc1ccc (cc1C (F) (F) F) -c1nc (no1) -c1ccc2nc[nH]c2c1) C (F) (F) F
Molecular Formula
C19H12F6N4O2
Molecular Weight
442.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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