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ASP-4058

ASP-4058 is a second-generation, orally bioavailable agonist selectively targeting S1P1 and S1P5 receptors. It demonstrates efficacy in preclinical models, notably ameliorating experimental autoimmune encephalomyelitis (EAE) in mice, supporting its research application in neuroinflammatory and autoimmune disease studies.

Product Specifications

CAS Number

952565-91-2

Product Name Alternative

ASP 4058, ASP4058, ASP-4058, LPLReceptor, LPL Receptor, S1P Receptor, S1P5, S1PReceptor, S1P1

Field of Research

Pharmacology & Drug Discovery

Purity

99.30% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.52 mM) ; DMSO:70 mg/mL (158.26 mM)

Smiles

C[C@H] (Oc1ccc (cc1C (F) (F) F) -c1nc (no1) -c1ccc2nc[nH]c2c1) C (F) (F) F

Molecular Formula

C19H12F6N4O2

Molecular Weight

442.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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