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ATX inhibitor 5

ATX inhibitor 5 is a potent, orally bioavailable small molecule targeting autotaxin with an IC50 of 15.3 nM. It has demonstrated anti-fibrotic efficacy in a CCl4-induced mouse model of hepatic fibrosis, making it a valuable research tool for studying ATX biology and liver disease pathogenesis.

Product Specifications

CAS Number

2402772-45-4

Product Name Alternative

Autotaxin, ATX inhibitor 5, ATX

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

98.77% (May vary between batches)

Solubility

DMSO:225 mg/mL (473.81 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.95 mM)

Smiles

FC (F) (F) c1cccc (Nc2ncnc3CCN (Cc23) C (=O) N\N=C\c2ccc (Cl) cc2) c1

Molecular Formula

C22H18ClF3N6O

Molecular Weight

474.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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