ATX inhibitor 5
ATX inhibitor 5 is a potent, orally bioavailable small molecule targeting autotaxin with an IC50 of 15.3 nM. It has demonstrated anti-fibrotic efficacy in a CCl4-induced mouse model of hepatic fibrosis, making it a valuable research tool for studying ATX biology and liver disease pathogenesis.
Product Specifications
CAS Number
2402772-45-4
Product Name Alternative
Autotaxin, ATX inhibitor 5, ATX
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.77% (May vary between batches)
Solubility
DMSO:225 mg/mL (473.81 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.95 mM)
Smiles
FC (F) (F) c1cccc (Nc2ncnc3CCN (Cc23) C (=O) N\N=C\c2ccc (Cl) cc2) c1
Molecular Formula
C22H18ClF3N6O
Molecular Weight
474.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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