AZD-5991
AZD-5991 is a potent and selective MCL-1 inhibitor that triggers Bak-dependent mitochondrial apoptosis in cancer cells. It is utilized in research for hematological malignancies like multiple myeloma and AML, as well as solid tumors such as triple-negative inflammatory breast cancer, with studies demonstrating activity in both in vitro and in vivo models.
Product Specifications
CAS Number
2143061-81-6
Product Name Alternative
AZD 5991, AZD5991, AZD-5991, Mcl-1
Field of Research
Cell Biology
Purity
98.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.44 mM) ; H2O:<0.1 mg/mL (insoluble) ; DMSO:200 mg/mL (297.5 mM)
Smiles
Cc1c-2c (CSCc3cc (CSc4cc (OCCCc5c (C (O) =O) n (C) c6c-2c (Cl) ccc56) c2ccccc2c4) n (C) n3) nn1C
Molecular Formula
C35H34ClN5O3S2
Molecular Weight
672.26
Storage Conditions
-20°C
Notes
For research use only.
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