AZD-5991
AZD-5991 is a potent and selective MCL-1 inhibitor that triggers Bak-dependent mitochondrial apoptosis in cancer cells. It is utilized in research for hematological malignancies like multiple myeloma and AML, as well as solid tumors such as triple-negative inflammatory breast cancer, with studies demonstrating activity in both in vitro and in vivo models.
Product Specifications
CAS Number
2143061-81-6
Product Name Alternative
AZD 5991, AZD5991, AZD-5991, Mcl-1
Field of Research
Cell Biology
Purity
98.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.44 mM) ; H2O:<0.1 mg/mL (insoluble) ; DMSO:200 mg/mL (297.5 mM)
Smiles
Cc1c-2c (CSCc3cc (CSc4cc (OCCCc5c (C (O) =O) n (C) c6c-2c (Cl) ccc56) c2ccccc2c4) n (C) n3) nn1C
Molecular Formula
C35H34ClN5O3S2
Molecular Weight
672.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb3089410 100 µg
Zebrafish MYOD1 Rabbit Polyclonal Antibody (Fluoro647)
Sign In for Pricing
View Details 
141800 200 µL
Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting Protein 4 (PIN4, EPVH, PAR14, PAR17, Parvulin)
Sign In for Pricing
View Details