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AZD4573

AZD4573 is a potent and selective CDK9 inhibitor with an IC50 below 4 nM, designed for transient target engagement. It is utilized in hematologic malignancy research, demonstrating activity in both in vitro assays and in vivo xenograft models for cancers like acute myeloid leukemia.

Product Specifications

CAS Number

2057509-72-3

Product Name Alternative

AZD-4573, AZD4573, AZD 4573, CDK9, CDK, Cyclin dependent kinase, Inhibitor, inhibit

Field of Research

Cell Biology

Purity

99.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.3 mM) ; DMSO:118.75 mg/mL (276.2 mM)

Smiles

CC (=O) N[C@@H]1CCC[C@@H] (C1) C (=O) Nc1cc (-c2cnn3CC (C) (C) Cc23) c (Cl) cn1

Molecular Formula

C22H28ClN5O2

Molecular Weight

429.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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