BACE-1 inhibitor 1
Compound 8a is a potent small molecule inhibitor of BACE-1, exhibiting an IC50 value of 56 nM. This inhibitor is a valuable research tool for studying Alzheimer's disease pathogenesis and for conducting in vitro enzymatic assays and cellular studies targeting beta-amyloid production.
Product Specifications
CAS Number
1262858-14-9
Field of Research
Neuroscience, Pharmacology & Drug Discovery; Cell Biology
Smiles
C (F) (F) [C@@]1 (N=C (N) COC1) C2=CC (NC (=O) C3=CC=C (Br) C=N3) =CC=C2F
Molecular Formula
C17H14BrF3N4O2
Molecular Weight
443.22
Storage Conditions
-20°C
Notes
For research use only.
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