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BACE-1 inhibitor 1

Compound 8a is a potent small molecule inhibitor of BACE-1, exhibiting an IC50 value of 56 nM. This inhibitor is a valuable research tool for studying Alzheimer's disease pathogenesis and for conducting in vitro enzymatic assays and cellular studies targeting beta-amyloid production.

Product Specifications

CAS Number

1262858-14-9

Field of Research

Neuroscience, Pharmacology & Drug Discovery; Cell Biology

Smiles

C (F) (F) [C@@]1 (N=C (N) COC1) C2=CC (NC (=O) C3=CC=C (Br) C=N3) =CC=C2F

Molecular Formula

C17H14BrF3N4O2

Molecular Weight

443.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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