BACE1-IN-1
BACE1-IN-1 is a potent and brain-penetrant inhibitor of BACE1, demonstrating IC50 values of 32 nM and 47 nM against human BACE1 and BACE2, respectively. It is a valuable research tool for in vitro and in vivo studies investigating the role of BACE in Alzheimer's disease pathogenesis.
Product Specifications
CAS Number
1310347-50-2
Field of Research
Cell Biology, Neuroscience
Smiles
C[C@@]1 (N=C (N) OCC1 (F) F) c1cc (NC (=O) c2ccc (cn2) C#N) ccc1F
Molecular Formula
C18H14F3N5O2
Molecular Weight
389.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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