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BACE1-IN-1

BACE1-IN-1 is a potent and brain-penetrant inhibitor of BACE1, demonstrating IC50 values of 32 nM and 47 nM against human BACE1 and BACE2, respectively. It is a valuable research tool for in vitro and in vivo studies investigating the role of BACE in Alzheimer's disease pathogenesis.

Product Specifications

CAS Number

1310347-50-2

Field of Research

Cell Biology, Neuroscience

Smiles

C[C@@]1 (N=C (N) OCC1 (F) F) c1cc (NC (=O) c2ccc (cn2) C#N) ccc1F

Molecular Formula

C18H14F3N5O2

Molecular Weight

389.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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