PROTAC Bcl2 degrader-1
PROTAC Bcl2 degrader-1 is a potent and selective degrader of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM) . This bifunctional molecule is a valuable chemical tool for investigating Bcl-2 family protein function and apoptosis in cancer research, applicable in both cellular and biochemical assays.
Product Specifications
CAS Number
2378801-85-3
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCOCCOCCNC (=O) CCCCC (=O) NCCN4C (=O) C5=CC=CC=6C (SC7=CC=C (Br) C=C7) =CC=C (C4=O) C56) C3C2=O) CC1
Molecular Formula
C45H45BrN6O10S
Molecular Weight
941.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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