BI-1408
BI-1408 is a potent γ-secretase modulator, exhibiting an IC50 of 0.04 μM against Aβ42 production. This small molecule inhibitor is a valuable research tool for in vitro and in vivo studies investigating Alzheimer's disease pathology and Notch signaling pathways.
Product Specifications
CAS Number
2231075-94-6
Product Name Alternative
γ-secretase, Aβ42, BI 1408, BI1408, BI-1408, Gammasecretase
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
97.91% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
N (C=1N=C2C (=CC=CN2N1) C3=C (C) C=C (F) C=C3) [C@H]4CC5=C (CC4) N (CC) N=C5
Molecular Formula
C22H23FN6
Molecular Weight
390.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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