BI-2852
BI-2852 is a potent, nanomolar-affinity small molecule inhibitor targeting the KRAS switch I/II pocket. It effectively blocks downstream signaling pathways and demonstrates antiproliferative activity in KRAS-mutant cell lines, making it a valuable tool for in vitro oncology research and signaling studies.
Product Specifications
CAS Number
2375482-51-0
Product Name Alternative
Inhibitor, inhibit, KRAS G12C, BI2852, BI-2852, BI 2852, Ras
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
97.77% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.87 mM) ; DMSO:55 mg/mL (106.47 mM)
Smiles
Cn1cnc (Cn2ccc3ccc (CNCc4[nH]c5ccccc5c4[C@H]4NC (=O) c5ccc (O) cc45) cc23) c1
Molecular Formula
C31H28N6O2
Molecular Weight
516.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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