Bio-THZ1
Bio-THZ1 is a biotin-conjugated derivative of THZ1, a potent, selective, and irreversible covalent inhibitor of CDK7 (IC50 = 3.2 nM) . This tool compound is widely used in proteomics and target engagement studies, facilitating research into transcription and cell cycle regulation in both cellular and animal models.
Product Specifications
CAS Number
1604811-14-4
Field of Research
Cell Biology
Smiles
[H][C@]12CS[C@@H] (CCCCC (=O) NCCOCCOCCOCCNC (=O) NCCCN (C) C\C=C\C (=O) Nc3ccc (cc3) C (=O) Nc3cccc (Nc4ncc (Cl) c (n4) -c4c[nH]c5ccccc45) c3) [C@@]1 ([H]) NC (=O) N2
Molecular Formula
C52H65ClN12O8S
Molecular Weight
1053.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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