Bitopertin (R enantiomer)
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-configuration isomer of Bitopertin, functioning as a potent and noncompetitive inhibitor of the glycine transporter 1 (GlyT1) with an IC50 of 25 nM. This compound is utilized in preclinical research to investigate GlyT1 function in neurological disorders, including schizophrenia, through in vitro binding assays and in vivo behavioral models.
Product Specifications
CAS Number
845614-12-2
Field of Research
Neuroscience
Smiles
C (=O) (C1=C (O[C@@H] (C (F) (F) F) C) C=CC (S (C) (=O) =O) =C1) N2CCN (CC2) C3=C (F) C=C (C (F) (F) F) C=N3
Molecular Formula
C21H20F7N3O4S
Molecular Weight
543.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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