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BLM-IN-1

BLM-IN-1 is a potent small-molecule inhibitor of the Bloom syndrome protein (BLM), exhibiting a KD of 1.81 μM and an IC50 of 0.95 μM. This compound triggers the DNA damage response, leading to apoptosis and cell cycle arrest in cancer cells, making it a valuable tool for oncology research in vitro.

Product Specifications

CAS Number

2056014-40-3

Field of Research

Cell Biology, Epigenetics & Chromatin

Smiles

CCN (CC) CCCNc1cc2nc3\C (CCn3c (=O) c2cc1F) =C\c1ccc (cc1) C (C) C

Molecular Formula

C28H35FN4O

Molecular Weight

462.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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