BLM-IN-1
BLM-IN-1 is a potent small-molecule inhibitor of the Bloom syndrome protein (BLM), exhibiting a KD of 1.81 μM and an IC50 of 0.95 μM. This compound triggers the DNA damage response, leading to apoptosis and cell cycle arrest in cancer cells, making it a valuable tool for oncology research in vitro.
Product Specifications
CAS Number
2056014-40-3
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
CCN (CC) CCCNc1cc2nc3\C (CCn3c (=O) c2cc1F) =C\c1ccc (cc1) C (C) C
Molecular Formula
C28H35FN4O
Molecular Weight
462.6
Storage Conditions
-20°C
Notes
For research use only.
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