BMS-654457
BMS-654457 is a potent and reversible small-molecule inhibitor of factor XIa (FXIa), exhibiting Kis of 0.2 nM and 0.42 nM against human and rabbit enzymes, respectively. It serves as a valuable research tool for investigating antithrombotic mechanisms in both in vitro biochemical assays and in vivo preclinical models.
Product Specifications
CAS Number
1004551-41-0
Field of Research
Metabolism Research
Smiles
C[C@]1 (C=2C (N[C@@H] (C1) C3=CC (=CC (NC (CC (C) C) =O) =C3) C4=C (C (O) =O) C=C (C (N) =O) C=C4) =CC=C (C (=N) N) C2) C5=CC=CC=C5
Molecular Formula
C36H37N5O4
Molecular Weight
603.71
Storage Conditions
-20°C
Notes
For research use only.
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