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BMT-124110

BMT-124110 is a potent and selective AAK1 inhibitor (IC50 = 0.9 nM) with demonstrated antinociceptive activity in vivo. It also inhibits the kinases BIKE (IC50 = 17 nM) and GAK (IC50 = 99 nM), making it a useful research tool for studying clathrin-mediated endocytosis, neuropathic pain, and viral entry mechanisms.

Product Specifications

CAS Number

1679371-59-5

Product Name Alternative

AAK1 (AP2 associated kinase 1), AAK1, AAK1 (AP2associatedkinase1), AP2 associated kinase 1, AP2associatedkinase1, BMT 124110, BMT124110, BMT-124110

Field of Research

Neuroscience

Purity

98.07% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (74.43 mM)

Smiles

N (C (C) =O) C=1C=C2C=3C (=CC (OC[C@@] (CC (C) C) (C) N) =CC3) OCC2=CN1

Molecular Formula

C21H27N3O3

Molecular Weight

369.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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