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BM 957

BM 957 is a potent small molecule inhibitor of the anti-apoptotic proteins Bcl-2 and Bcl-xL, exhibiting sub-nanomolar binding affinity and low nanomolar cellular activity. This compound is a valuable research tool for investigating apoptosis mechanisms and has been utilized in both in vitro and in vivo cancer research models to study tumor cell survival and therapy resistance.

Product Specifications

CAS Number

1391107-54-2

Field of Research

Cell Biology

Smiles

C (O) (=O) C=1C (=C (N (CC) C1C) C2=CC=C (Cl) C=C2) C3=CC (=CC=C3) N4CCN (CC4) C5=CC=C (NS (=O) (=O) C6=CC (S (C (F) (F) F) (=O) =O) =C (N[C@H] (CCN7CCC (O) CC7) CSC8=CC=CC=C8) C=C6) C=C5

Molecular Formula

C52H56ClF3N6O7S3

Molecular Weight

1065.68

Storage Conditions

-20°C

Notes

For research use only.

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