BPH-1358 free base
BPH-1358 free base (NSC50460) is a dual inhibitor of bacterial undecaprenyl diphosphate synthase (UPPS; IC50 = 110 nM) and human farnesyl diphosphate synthase (FPPS; IC50 = 1.8 μM) . It exhibits in vitro antibacterial activity against Staphylococcus aureus with an MIC of approximately 250 ng/mL, making it a useful research tool for studying bacterial cell wall biosynthesis and isoprenoid pathway inhibition.
Product Specifications
CAS Number
801985-13-7
Field of Research
Infectious Disease & Virology
Smiles
N (C (=O) C1=CC=C (C=C1) C2=CC=C (C (NC3=CC (=CC=C3) C=4NCCN4) =O) C=C2) C=5C=C (C=CC5) C=6NCCN6
Molecular Formula
C32H28N6O2
Molecular Weight
528.6
Storage Conditions
-20°C
Notes
For research use only.
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