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BPH-1358 free base

BPH-1358 free base (NSC50460) is a dual inhibitor of bacterial undecaprenyl diphosphate synthase (UPPS; IC50 = 110 nM) and human farnesyl diphosphate synthase (FPPS; IC50 = 1.8 μM) . It exhibits in vitro antibacterial activity against Staphylococcus aureus with an MIC of approximately 250 ng/mL, making it a useful research tool for studying bacterial cell wall biosynthesis and isoprenoid pathway inhibition.

Product Specifications

CAS Number

801985-13-7

Field of Research

Infectious Disease & Virology

Smiles

N (C (=O) C1=CC=C (C=C1) C2=CC=C (C (NC3=CC (=CC=C3) C=4NCCN4) =O) C=C2) C=5C=C (C=CC5) C=6NCCN6

Molecular Formula

C32H28N6O2

Molecular Weight

528.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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