BPN-15606
BPN-15606 is a potent, orally bioavailable γ-secretase modulator that selectively reduces Aβ42 and Aβ40 levels in vitro (IC50 7 nM and 17 nM in SHSY5Y cells) and in the CNS of rodent models. This profile supports its use in research on Alzheimer's disease pathogenesis and amyloid-related mechanisms.
Product Specifications
CAS Number
1914989-49-3
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
COc1nc (ccc1-n1cnc (C) c1) -c1cc (C) c (N[C@@H] (C) c2ccc (F) cc2) nn1
Molecular Formula
C23H23FN6O
Molecular Weight
418.47
Storage Conditions
-20°C
Notes
For research use only.
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